Endothelial and mast cells labeled positive for 5HT1B serotonin receptors and spermatozoa
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چکیده
Serotonin concentration, synthesis, cell origin and targets in the rat caput epididymis 1 during sexual maturation and variations associated with adult mating status: 2 Morphological and biochemical studies 3 4 Running Head: Serotonin system in the rat epididymis 5 FRANCISCO JIMÉNEZ-TREJO, MIGUEL TAPIA-RODRÍGUEZ, DANIEL B.C. 6 QUEIROZ, PATRICIA PADILLA, MARIA CHRISTINA W. AVELLAR, PATRICIA RIVAS 7 MANZANO, GABRIEL MANJARREZ-GUTIÉRREZ AND GABRIEL GUTIÉRREZ8 OSPINA 9 10 Department of Cell Biology and Physiology, Biomedical Research Institute, National 11 Autonomous University of Mexico, Mexico City, 04510. 12 Department of Pharmacology, Section of Experimental Endocrinology, Universidade Federal de 13 São Paulo-Escola Paulista de Medicina, São Paulo, SP, Brazil 04044-020. 14 Department of Reproductive Biology, Faculty of Sciences, National Autonomous University of 15 Mexico, Mexico City, 04510. 16 Unit of Medical Investigation in Neurological Diseases, XXI Century National Medical Center, 17 Mexican Institute of Social Security, Mexico City, 06703. 18 19 These authors contributed equally to the present work. 20 21 Correspondence to: 22 * Dr. Gabriel Gutiérrez-Ospina, Department of Cell Biology and Physiology, National 23 Autonomous University of Mexico, Ciudad Universitaria, Mexico City, 04510. Phone: (+52) (55) 24 5622-3195. Fax: (+52) (55) 5622-3897. E-mail: [email protected] 25 26 Supported by: CONACyT grants 38615N and J28035N, PAPITT, UNAM grants IN203702 and 27 IN232604, FAPESP grants 99/09491-8 and 00/09381-7. Fellowships supported by FAPESP 28 (DBCQ), by CONACyT (FJT and MTR) and Telmex Foundation (FJT). 29 30
منابع مشابه
Serotonin concentration, synthesis, cell origin, and targets in the rat caput epididymis during sexual maturation and variations associated with adult mating status: morphological and biochemical studies.
The caput epididymis of some mammals contains large quantities of serotonin whose origin, targets, and physiological variations have been poorly studied. We combined morphological and biochemical techniques to begin approaching these aspects of serotonin in the rat caput epididymis. Serotonin immunostaining was detected in mast, epithelial, and neuroendocrine cells. Epithelial cells displayed i...
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